产品货号:
Z10412
中文名称:
ACVR2B抗体
英文名称:
Anti-ACVR2B Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ACVR2B Antibody |
指标别名 | ACTRIIB;ActR-IIB;MGC116908 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,ELISA |
基因名称 | ACVR2B |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human AVR2B protein. |
计算分子量 | 58KD |
成分 | Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide. |
纯化方式 | AVR2B antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Activin receptor type-2B is a protein that in humans is encoded by the ACVR2B gene.Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins.Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors.These receptors are all transmembrane proteins,composed of a ligand-binding extracellular domain with cysteine-rich region,a transmembrane domain,and a cytoplasmic domain with predicted serine/threonine specificity.Type I receptors are essential for signaling;and type II receptors are required for binding ligands and for expression of type I receptors.Type I and II receptors form a stable complex after ligand binding,resulting in phosphorylation of type I receptors by type II receptors.Type II receptors are considered to be constitutively active kinases.This ACVR2B gene encodes activin A type IIB receptor,which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. |
Uniprot ID | Q13705 |
基因名全称 | Activin receptor type-2B |
蛋白名全称 | Activin receptor type-2B |
推荐稀释比 | WB 1:500~2000 ELISA 1:5000~20000 |
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